Revival of Temperament in Modern Biochemistry through CHON Balancing Theory

By Dr. Nisar Ahmed Gorar

Abstract

For centuries, ancient physicians explained health and disease through the balance of four temperaments — Hot, Cold, Dry, and Moist.

Modern science long dismissed these as metaphysical concepts without measurable basis.

However, with the advent of Biochemistry, Molecular Biology, Artificial Intelligence, and CHON Balancing Therapy,

these ancient terms have re-emerged with precise biochemical meaning.

This paper explores how the CHON model (Carbon, Hydrogen, Oxygen, Nitrogen) provides a molecular foundation for classical temperaments and establishes a unified scientific bridge between traditional medicine and modern biochemistry.

1. Introduction

The classical Unani and Greek systems of medicine were built upon the concept of temperament (Mizaj) — a framework that viewed the human body as a dynamic equilibrium of qualities: heat, coldness, moisture, and dryness.

In this view, every organ, fluid, and emotion corresponded to a unique balance of these four primary qualities. 

Modern medical science, dominated by reductionism and molecular focus, initially rejected these terms as unscientific.

But as understanding of atomic structure, redox biology, metabolic pathways, and neurochemical regulation evolved,

scientists discovered that these very qualities correspond to measurable elemental patterns and energy states within the human body.

1. The CHON Paradigm: Elemental Foundation of Life

All living organisms are composed primarily of four elements — Carbon (C), Hydrogen (H), Oxygen (O), and Nitrogen (N).

These elements are not only structural but functional determinants of life and metabolism. It should be noted that these elements don’t work or influence alone but with mutual hormoney and with the help of other elements which work as co factor and support. for example Sulfur, Phosphorus megnessium, calcium etc

Element Dominant Classical Temperament Biochemical Role

Carbon (C) Dry Provides structure, detoxification, stability, and rigidity

Hydrogen (H) Moist Maintains fluidity, hydration, and energy transfer

Oxygen (O) Hot Drives oxidation, metabolism, and energy production

Nitrogen (N) Cold Promotes rest, calmness, and neural regulation

Each element expresses one of the classical temperamental qualities — meaning the ancient framework of Hot, Cold, Dry, Moist was in fact an early qualitative observation of CHON-driven biochemical states.

1. CHON Balancing Therapy: The Bridge Between Tradition and Biochemistry

CHON Balancing Therapy, developed and advanced through the work of Dr. Nisar Ahmed Gorar, integrates classical temperament theory with molecular and mitochondrial science.

It proposes that disease arises when one or more of the CHON elements become excessive or deficient, disturbing the internal equilibrium of the body.

Element Excess Manifestation Deficiency Manifestation

Oxygen (O) Heat, inflammation, hypermetabolism Fatigue, hypoxia

Nitrogen (N) Coldness, depression, low motivation Nervous excitation, insomnia

Hydrogen (H) Swelling, emotional hypersensitivity Dryness, irritability

Carbon (C) Stiffness, constipation, rigidity Weakness, lack of form or tone

The therapy aims to restore CHON balance using dietary, environmental, and pharmacological adjustments — a modern biochemical restatement of temperamental correction.

1. Artificial Intelligence and Molecular Verification

With the rise of AI-based biochemical modeling, we now have tools to validate temperament on a quantitative scale.

Modern AI systems analyze molecular formulas to determine oxidative (O), hydric (H), carbonic (C), and nitrogenic (N) tendencies of compounds —

precisely reflecting what ancient systems called hot, moist, dry, and cold properties.

For example:

A compound with a high O:H ratio demonstrates oxidative heat.

A compound rich in N:C ratio shows cooling and stabilizing tendencies.